76EVALUATION OF TARENNA ASIATICA (L.) O. KTZE. EX K. SCHUM. FRUIT EXTRACT AGAINST INFLAMMATIONTarenna asiatica fruits were analysed for the validation of anti-inflammatory effects reported in the ethnobotanical literature. The plant is widely used as a traditional medicine to treat several disorders and diseases such as external ulcers, boils, sores, skin diseases, paralysis, wound healing etc. The anti-inflammatory activity of acetone extract of fruit was also shown by significant (p<0.05, 0.01, 0.001) reduction of paw linear diameter after 4 hours in both carrageenan (5.52 ± 0.21 mm) and egg albumin (4.81 ± 0.37 mm) induced paw oedema in rats at a dose of 200 mg/kg). The study on cotton pellet induced granuloma in rats has shown significant reduction in weight of granuloma (67.52%) by acetone extract of fruit at 200 mg/kg. Hence, it can be concluded that the acetone extract of T. asiatica fruit possesses significant anti-inflammatory effects and can be used as a natural source for anti-inflammatory drug.dr.karthikkumaran@gmail.comResearch522015Anti-inflammatory,Carrageenan,Carboxymethyl cellulose,Cotton pellet granuloma,Tarenna asiaticaKarthikkumaran S,Parimelazhagan TDepartment of Botany, Arulmigu Palani Andavar Arts College For Women (Autonomous), Palani - 624 615, Tamil Nadu, India.,Department of Botany, Bharathiar University, Coimbatore - 641 046, Tamil Nadu, India.